Open access
Aug 2026
Democratizing LYTACs-A Modular Click Chemistry Platform for the Rapid Assembly of Lysosome-Targeting Chimeras.
A simple, rapid, and modular click chemistry platform for the generation of CI-M6PR-binding LYTACs, which utilizes only commercially available reagents and standard laboratory equipment and allows for the conversion of virtually any antibody into a LYTAC.
Peter A. Szijj, Sherry Li, M. Gilbert et al.
· ACS Chemical Biology · 0 citations