Open access
Aug 2026
A metabolite morphogen coordinates multicellular development in Bacillus subtilis
It is shown that biofilm formation and sporulation instead diverge along a branched pathway, which emerges through a branched developmental program in which sporulating cells generate the cue that creates the biofilm-producing lineage via cell-cell communication through repurposing of a canonical intracellular metaboli...
Taylor B. Updegrove, V. Pande, Fukang She et al.
· Science Advances · 1 citation