Author

M. Grosser

3 papers indexed here

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Open access Sep 2026

Predicting risk of ischemic stroke: A transformer model using genomic data.

BACKGROUND AND OBJECTIVE Ischemic stroke is a leading cause of mortality and long-term disability worldwide. Genetic factors contribute to IS susceptibility, yet conventional polygenic risk score approaches are primarily based on additive effects and may not fully capture non-linear relationships or positional context...

Yue Yang, Kai-Rui Guo, Zhen Fang et al. · Computer Methods and Program... · 0 citations

#artificial intelligence Preprint Sep 2026

Large Language Model Agents for Evidence Based Genetic Disease Severity Classification

An autonomous AI agent integrating Reasoning and Acting with Retrieval-Augmented Generation with Retrieval-Augmented Generation is developed to classify 10,211 Human Phenotype Ontology terms, enabling standardized panel design by providing reliable, automated classification supported by direct evidence.

Tohid Ghasemnejad, A. Argha, M. Grosser et al. · 0 citations

Preprint Jul 2026

Harmonised benchmarking of foundation models for single-cell and spatial transcriptomics reveals context-dependent generalisation

This benchmark provides practical guidance for model selection and argues that future models should be judged by biological generalisation, interpretability and perturbation-grounded validity, not by scale or leaderboard performance alone.

S. Chen, Roxana Zahedi, Lucy Chhuo et al. · 0 citations