Background In the DeLLphi-304 trial, at a median follow-up of <12 months, tarlatamab significantly improved overall survival (OS), progression-free survival (PFS), and patient-reported outcomes (PROs), and demonstrated a favorable safety profile versus chemotherapy. We report efficacy and safety outcomes after extended...
C. Rudin, M.-J. Ahn, M. Schuler et al.· Annals of Oncology· 0 citations
Sarcopenia is increasingly recognized as a potential prognostic factor in patients with cancer, but its clinical significance in HR+/HER2− metastatic breast cancer treated with CDK4/6 inhibitors remains uncertain. This study investigated the association between CT-defined sarcopenia and clinical outcomes in this po...
Zeynep Alaca Topçu, Zehra Sucuoğlu İşleyen, Ismail Yurtsever et al.· Frontiers in Medicine· 0 citations
An elevated pretreatment CONUT score was associated with shorter overall survival in this selected chemotherapy-treated cohort, and as a readily available laboratory-based index, CONUT may provide additional prognostic information; however, prospective studies are needed to determine whether it adds value beyond establ...
Zeynep Alaca Topçu, Serhat Demirer, T. Baydaş et al.· Medicina· 0 citations
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