Open access
Sep 2026
Barrier immune memory is programmed by intestinal epithelial cell presentation of cytosol-delivered bacterial antigens
Antigen compartmentalization is known to influence CD4 and CD8 T cell recognition but its impact on immune responses to different antigens expressed by the same pathogen is poorly understood. By tracking the clonal CD4 T cell response to a single epitope shuttled between different virulence proteins of Citrobacter rode...
C. Wilson, M. P. Acharya, Laura Karsch et al.
· Nature Immunology · 1 citation