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Open access Oct 2026

Striatal network dysfunction underlying speech impairment in early Parkinson’s disease

The pathophysiology underlying Parkinson’s disease (PD) speech impairments and its potential sex differences remain unclear. We investigated sex-specific alterations in speech and striato-cortical networks in 104 patients with early PD (68M/36F), and 44 healthy controls (23M/21F), using quantitative speech markers and...

Caitlin Paige Rogers, Sandy Mournet, C. Galléa et al. · 0 citations
Open access Jul 2026

Episodic memory ERPs reflect preclinical Alzheimer’s disease progression

Background Alzheimer’s disease (AD) neuropathology emerges decades before symptoms, requiring sensitive, non-invasive markers for early diagnosis. We investigated behavioural and EEG markers of episodic memory in cognitively normal older adults at-risk for AD. Methods Forty-five INSIGHT-preAD cohort participants (15 pr...

F. Raposo Pereira, Maximilien Chaumon, Bruno Dubois et al. · 0 citations

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