Open access
Jul 2026
Phenotypic screening for small molecules that lower PrP in cultured cells
Findings highlight the challenges associated with mechanism-agnostic phenotypic screening for PrP-lowering compounds and support prioritizing compounds with known mechanisms of action and support prioritizing compounds with known mechanisms of action.
Jeannine A. Frei, A. Reidenbach, Leo Xu et al.
· Molecular and cellular neuro... · 0 citations