OBJECTIVE
Focal cortical dysplasia (FCD) is a common cause of drug-resistant epilepsy in children and adults and exhibits substantial clinical and histopathological heterogeneity. However, morphological classification alone does not fully explain variability in epileptogenicity, disease severity, or treatment response....
Shivani Sonawane, M. Hendrych, M. Ručková et al.· Epilepsia· 0 citations
Glioblastoma (GBM) is the most aggressive primary brain tumor in adult patients and is characterized by significant cellular heterogeneity and complex interactions between tumor cells and the tumor microenvironment. Extracellular vesicles (EVs) and the microRNAs (miRNAs) they carry are important mediators of intercellu...
Kamila Součková, F. Siegl, Martina Hýžďalová et al.· Klinicka onkologie· 0 citations
This narrative educational review aims to provide a comprehensive overview of recent advances in the understanding of ovarian cancer pathogenesis, the molecular mechanisms driving tumor progression, and the multifaceted role of the immune system in disease development and therapeutic response.
B. Vavrušáková, R. Bartošová, M. Hendrych et al.· Discover Oncology· 0 citations
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