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Open access Sep 2026

Tumor genomic landscape of older patients with metastatic breast cancer☆

Background Metastatic breast cancer (MBC) in older patients has distinct clinical and histologic characteristics. Elucidating the genomic basis of MBC helps identify potential therapeutic targets to improve outcomes for older patients with MBC. Patients and methods Using a prospective database and targeted DNA sequenci...

H. Gupta, K. Brantley, T. Grinda et al. · 0 citations
Review Sep 2026

Association of immune and proliferation gene signatures and stromal tumor-infiltrating lymphocytes with clinical outcomes in patients with stage I triple-negative breast cancer.

BACKGROUND One-third of patients with triple-negative breast cancer (TNBC) are diagnosed with stage I tumors. Biomarkers to stratify prognosis in this setting remain a major unmet need. METHODS Tissue samples and clinicopathologic data were retrieved from consecutive patients with stage I TNBC (defined as ER <10% and...

P. Tarantino, Tian-Yu Li, Laia Paré Brunet et al. · 0 citations

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