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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

M. Hysong

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Open access Sep 2026

Phenome- and laboratory-wide meta-analyses of sickle cell trait reveal multi-system disease associations

Sickle cell trait (SCT) is increasingly recognized as a risk factor for adverse health outcomes. We utilized three large US electronic health record-based biobanks (Vanderbilt University Medical Center’s BioVU, Penn Medicine Biobank, and All of Us) to conduct phenome-wide association (PheWAS) and clinical laboratory-wi...

M. Hysong, Megan M. Shuey, T. Miller-Fleming et al. · 0 citations
Review Open access Aug 2026

Practical considerations for social determinant-based disease prediction in the All of Us research program

It is shown that requiring sufficient individual-level SDoH survey data results in significant selection bias and sample reduction in AoU, and that area-level SDoH metrics contribute to disease prediction independently of individual-level measures.

M. Hysong, A. Manning, Michael D. Green et al. · 1 citation

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