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Author

M. Ihara

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Review Aug 2026

Arterial spin labeling-derived cerebral blood flow as a translational biomarker and candidate surrogate endpoint for cognitive impairment.

PURPOSE OF REVIEW Arterial spin labeling (ASL) MRI noninvasively quantifies cerebral blood flow (CBF), but its role as a mechanistic biomarker and surrogate endpoint in trials of cognitive impairment remains undefined. This review evaluates evidence linking regional CBF to cognition across Alzheimer's disease, mild cog...

Satoshi Hosoki, P. Sachdev, M. Ihara · 0 citations

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