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M. Jeleń

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Open access Jul 2026

Novel Triazole–Diquinothiazine Hybrids Modulating Apoptosis and Stress Pathways in Colorectal Cancer Cells

Among the tested derivatives, compound B5 demonstrated the most favorable biological profile, characterized by a more pronounced biological response in HCT116 cells than in BEAS-2B cells, increased ROS generation, reduced MDM2 expression, and a marked induction of early apoptosis.

Klaudia Giercuszkiewicz-Haśnik, Magdalena Skonieczna, Beata Morak-Młodawska et al. · 0 citations