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Moonseong Jeong

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Open access Oct 2026

Integration of single cell omics with biobank data discovers allele-specific trans effects of SREBF1 on adipocyte expression of nearly 100 genes

The heritability of epigenetic sites around SAT adipocyte marker genes is enriched for abdominal obesity, and that these cell-type markers are also enriched for central pathways of adipocyte function, indicating widespread cell-type level cis-type level trans effects on highly common CMDs.

M. G. Sukhatme, A. Kar, Seung Hyuk T. Lee et al. · 0 citations
Open access Aug 2026

A biobank-scale method for learning modulators of gene-environment interaction underlying human complex traits from multiple environmental exposures.

Efficient multi-eNvironmental Gene-environment Interaction iNference Estimator (ENGINE), a supervised variance-component framework that learns an embedding that combines multiple environmental exposures while jointly estimating additive, G×E, and heteroskedastic noise components, making polygenic G×E analysis tractable...

Zheng-Tong Liu, Arush Ramteke, Aakarsh Anand et al. · 0 citations

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