Open access
Aug 2026
Prolonged SARS-CoV-2 infection in hematologic malignancies: clinical impact, risk factors and intra-host viral evolution
Viral intra-host mutations across the entire viral genome, predominantly within the spike were detected in most patients with prolonged COVID-19, especially in those who received anti-SARS-CoV-2 mAb as sotrovimab and tixagevimab/cilgavimab and these substitutions are associated with reduced viral susceptibility.
M. Jiménez, Cristina Andrés, A. González-Sánchez et al.
· Frontiers in Immunology · 0 citations