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Open access Sep 2026

Diagnostic utility of targeted flow cytometry in genetically confirmed inborn errors of immunity: a 20-year single-center experience

Inborn errors of immunity (IEIs) are a heterogeneous group of genetic disorders in which timely diagnosis is essential for appropriate treatment and improved clinical outcomes. Although next-generation sequencing provides definitive molecular confirmation, it is often time-consuming, costly, and may not identify al...

Özgen Soyöz, Figen Çelebi Çelik, M. Kaya et al. · 0 citations
Open access Aug 2026

Early-Life Wheezing and Atopic Burden Are Associated with Treatment-Defined Asthma Severity and Control in School-Age Children: A Two-Center Cross-Sectional Study

Background: Childhood asthma is clinically heterogeneous, yet simple clinical approaches for describing concurrent disease burden are limited. We tested whether a two-axis phenotype matrix—built from early-onset and/or high-burden wheeze and atopic load—is associated cross-sectionally with treatment-defined severity an...

M. Kaya, A. Sefer, S. Baysal et al. · 0 citations

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