Chimeric antigen receptor (CAR)-based immunotherapy has transformed cancer treatment by enabling engineered immune cells to selectively recognize and eliminate malignant targets, with CAR-T cells establishing the first major clinical success in this field. However, severe associated toxicities, logistical complexitie...
A. Bahr, Youssef Basem, Amani Alhejely et al.· Frontiers in Genome Editing· 0 citations
Diabetes mellitus is one of the biggest health problems in the world, increasingly linked to complications in multiple organs, including significant cardiopulmonary dysfunction. Agonists of the glucagon-like peptide-1 (GLP-1) receptor provide efficient glycemic control; however, their accessibility remains limited in...
Amal Naif Alshammari, Iman K. Abdel Gadir, Amal A. Abdulbaqi et al.· Journal of King Saud Univers...· 0 citations
The graphical abstract displays generalized information regarding the source and application of phages. According to the figure, natural water bodies and wastewater treatment plants are considered to be the major sources of lytic phages. These phages can be utilized for various activities, including lowering the bact...
S. Al-maaqar, Wael A. Alsubhi, Zakia F. Albalawy et al.· Water Science & Technolo...· 0 citations
From the current findings, curcumin has multiple therapeutic targets as an alternative to liraglutide and may possess the capacity to modulate neuroimmune dysfunction in diabetes by protecting the spleen–brain axis through JAK2/STAT3 modulation.
M. Khormi, Amal Naif Alshammari, R. A. Hegazy et al.· Pharmacognosy Magazine· 0 citations
Findings demonstrate the fenugreek seed extract’s in vitro antioxidant activity, preferential cytotoxicity toward the tested cancer cell lines, and inhibitory effects on pancreatic lipase and carbohydrate-digesting enzymes.
N. H. Aljarba, M. Khormi, Hamida Hamdi et al.· BioResources· 0 citations
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