Open access
Jul 2026
Neu1 deficiency is associated with reduced nicotine responsiveness and dopamine D3 receptor downregulation in zebrafish
It is suggested that Neu1-mediated PSA degradation may modulate dopamine D3 receptor-dependent nicotine sensitivity and contribute to reduced PSA levels and altered dopamine D3 receptor-related signaling, thereby influencing the threshold for nicotine-induced neural and behavioral activation.
Sumomo Tsuji, Haruka Ego, Ryota Shimizu et al.
· Fish Physiology & Biochemist... · 0 citations