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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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M. Koptyra

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Open access Aug 2026

A patient-derived tumoroid platform for NF1 low-grade glioma shows myeloid evolution and shifting metabolic dependencies during in vitro culturing

About 10–15% of individuals with Neurofibromatosis Type 1 develop a low-grade glioma (LGG) within the optic pathway, and an additional 3–5% of individuals develop LGG outside of the optic pathway. In recent years molecular analysis has greatly enhanced our understanding of what drives these NF1 LGG; however, to date...

David R. Beale, Isabella A DiStefano, Stephanie N. Brosius et al. · 0 citations

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