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Author

M. Krupovic

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Review Open access Sep 2026

Why did some viruses evolve to be giants while others did not?

Viruses are ubiquitous mobile genetic elements that are obligate symbionts of cellular life forms and replicate exclusively within host cells. The current taxonomy of viruses includes 10 realms (the top rank taxon), 8 of which have small genomes in the range of one to about 60 kilobases and commensurately small virions...

E. Koonin, M. Krupovic · 0 citations
Open access Aug 2026

Loss of replication and transcription systems accompanying transition to nucleus-dependent replication in “Ariadnavirales”, a proposed new order in nucleocytoviricot class Megaviricetes

Sicyoidochytrium minutum DNA virus (SmDNAV) was isolated several years ago from a protist host of family Thraustochytriaceae of the class Labyrinthulomycetes. This virus shared little similarity to other viruses in gene content and protein sequences, albeit seemingly belonging to the phylum Nucleocytoviricota. By exten...

N. Yutin, Y. Wolf, M. Krupovic et al. · 0 citations
Open access Aug 2026

Molecular architecture of colossal surface layers from hyperthermophilic archaea

Surface layers (S-layers) are paracrystalline protein lattices that form the outermost layer of the cell envelope in most archaea, providing structural support, protecting against external insults, and co-ordinating interactions with their environment. Despite their widespread occurrence, the molecular and structural d...

I. Caspy, V. Cvirkaite-Krupovic, Sofie van Dorst et al. · 0 citations
Open access Aug 2026

Coupling of stable isotope probing and metagenomics reveals the diversity of viruses infecting formatotrophs during anaerobic digestion process

This study demonstrates the power of SIP-viromics for resolving virus-host associations in complex anaerobic communities, linking viral diversity directly to metabolically active formatotrophic and methanogenic guilds.

Vuong Quoc Hoang Ngo, Caroline Talleu, François Enault et al. · 0 citations

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