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Open access Sep 2026

Type 2 immune history trains lung macrophages for viral disease tolerance.

Severe respiratory viral disease varies widely among individuals and often reflects immunopathology rather than inadequate pathogen control, suggesting that previous immune history can prime the lungs towards disease tolerance. Here we show that nerve- and airway-associated macrophages (NAMs), a subset of interstitial...

P. Damani-Yokota, Y. Yordanov, Eduardo D. Bernier et al. · 0 citations

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