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Open access Oct 2026

Intragenomic conflict between transformation and prophage explains taxon-specific DNA acquisition.

The activation of many chromosomally integrated mobile genetic elements by RecA-DNA nucleoprotein filaments may represent an adaptation to evading deletion through homologous recombination. Consistent with bacterial transformation facilitating such eliminations of inserted viral DNA, cross-taxa comparisons found isolat...

M. Kwun, N. Croucher · 0 citations
#artificial intelligence Open access Sep 2026

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

ABSTRACT The prevalence of antimicrobial resistance (AMR) within the common bacterial pathogen Streptococcus pneumoniae makes it a priority for the development of new antibiotics. While artificial intelligence (AI) has recently boosted phenotype‐based repurposing of drugs for other human pathogens, this remains to be i...

Joshua S. Fitch, Muhammad D. Ariadi, M. Kwun et al. · 1 citation

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