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Author

M. Lahmouad

1 paper indexed here

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Open access Sep 2026

Imatinib Resistance in Chronic Myeloid Leukemia Is Associated with Distinct Metabolic, Oxidative, and Autophagic Adaptations in K562-Derived Cell Sublines

Background/Objectives: Chronic myeloid leukemia (CML) is a hematopoietic stem cell malignancy initiated by the BCR::ABL1 oncoprotein. Although tyrosine kinase inhibitors (TKIs) have revolutionized CML therapy, resistance remains a major clinical challenge. Emerging evidence suggests that metabolic reprogramming contrib...

Ezzahra Rachid, M. Lahmouad, Rawane Bellemrrabet et al. · 0 citations

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