Author

M. Lauth

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#machine learning Preprint Sep 2026

A Federated Artificial Intelligence Framework for Optimizing Pancreatic Cancer Treatment - Strategy Update

While a centralized approach involving patient consent to collect and analyze data centrally would theoretically offer the best data quality and predictive performance, it is not always feasible in practice. Federated Learning (FL) architectures have shown to be a very promising approach to use and access distributed d...

Anne-Christin Hauschild, Amirreza Aleyasin, N. Beyer et al. · 0 citations

Open access Aug 2026

Small-Molecule-Mediated Depletion of the Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1B (DYRK1B) Protein Scaffold

Members of the DYRK kinase family have been implicated in the regulation of key metabolic processes. In particular, DYRK1B plays a central role in hepatic lipid metabolism and fatty liver disease. Notably, these functions depend not only on the enzyme’s catalytic activity but also on scaffolding properties. Consequentl...

Miriam S. Ems, Mattias F. Lindberg, Till Adhikary et al. · ACS Pharmacology & Translati... · 0 citations