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Review Open access Sep 2026

Cancer genomic data systems in precision oncology: from integration to clinical implementation.

Cancer genomic data sharing is a core pillar of precision oncology, underpinning reproducibility, scalability, and equity. The ability to discover, access, integrate, interpret, and reuse cancer 'omics data is a key determinant of precision oncology's value and benefit at scale. This work has been conducted as part of...

D. Torrents, Oliver Hofmann, Karen A. Cranston et al. · 1 citation
Open access Aug 2026

Diagnostic regulatory pathways are an underrecognized bottleneck in precision oncology clinical trials: Real-world evidence across Europe.

PURPOSE Using real-world data (RWD), we assessed the impact of diagnostic regulatory pathways on activation timelines and biomarker testing implementation in biomarker-driven clinical trials across Europe. METHODS RWD from 132 Clinical Performance Study Applications (PSAs) and Ethics Committee (EC) submissions across...

Sarah Hersey, Haydar Çelik, Steven T. Rosen et al. · 0 citations

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