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Author

M. Laws

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Sep 2026

The aryl hydrocarbon signaling pathway in the ovary changes throughout reproductive aging and in response to a mixture of phthalates over time in mice.

Phthalates are plasticizers and solvents used in numerous consumer products. Exposure to a phthalate mixture (Mix) alters estrous cyclicity, fertility indices, ovarian follicle dynamics, and steroidogenesis. In cultured antral follicles, phthalates alter the aryl hydrocarbon receptor (AHR) pathway, which is known for e...

A. E. Dean, R. Santacruz-Márquez, A. Safar et al. · 0 citations
Open access Aug 2026

Chronic Di(2-ethylhexyl) phthalate and Diisononyl phthalate Exposure Impairs Uterine Endometrial Glycogen Metabolism in Mice.

Results show that phthalates alter endometrial glycogen levels and expression of key enzymes, which are consistent with altered glycogen metabolism, which could alter endometrial glucose metabolism.

P. Zarei, Isabella Raneri, Garima Thapa et al. · 0 citations
Open access Jul 2026

Acute Exposure to Di(2-ethylhexyl) Phthalate or Diisononyl Phthalate Leads to Increased Inflammation and Oxidative Stress in the Uteri of Mice.

It is demonstrated that acute exposure to DEHP and DiNP induces uterine inflammatory and oxidative stress responses, with distinct dose-dependent effects for each phthalate.

Adriana Andrus, L. Y. Parra-Forero, Coba N Sexton et al. · 1 citation

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