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Author

M. Lemaître

2 papers indexed here

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Open access Aug 2026

MBNL depletion drives stem cell fusion and immature myonuclear states in myotonic dystrophy type 1

Myotonic dystrophy type 1 is caused by the expression of expanded CTG repeats in the DMPK gene and the resulting loss of function of MBNL protein. Affected skeletal muscle displays abundant centrally located nuclei despite limited immune-cell–associated fibre necrosis, complicating interpretation of muscle damage and r...

Vanessa Todorow, X. Lornage, Shinichiro Hayashi et al. · 0 citations
Open access Aug 2026

Axonopathy in Duchenne Muscular Dystrophy limits microdystrophin gene therapy efficacy

DMD is redefined as an integrated motor unit pathology, thereby underscoring the absolute necessity of implementing combined therapeutic strategies that target both the muscle and the peripheral nervous system.

Aly Bourguiba-Villeneuve, Maxime Gelin, Aurélie Fail et al. · 0 citations

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