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M. Leutzsch

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Open access Sep 2026

Intramolecular Nickel-Catalyzed Reductive Coupling: Enantioselective Synthesis of Tetrahydroisoquinolines and Related Heterocycles.

The P-chiral phosphine AntPhos was found to be the ligand of choice for nickel-catalyzed intramolecular reductive coupling reactions of 5-amino substituted 2,4-dienoates bearing a tethered aldehyde. This approach to heterocyclic compounds has little precedent in the literature; it provides, inter alia, ready access to...

Thilo Bender, M. Leutzsch, Yannik Sell et al. · 0 citations

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