117 Transcript-resolved mapping of the m6A RNA modification landscape in glioma using nanopore direct RNA sequencing
Glioblastoma (GBM) remains uniformly fatal despite multimodal therapy. While DNA methylation profiling has transformed brain tumour classification, post-transcriptional RNA modifications remain comparatively underexplored. N6-methyladenosine (m6A) is the most abundant internal RNA modification and regulates splic...