Association of depressive symptoms with sweat chloride variability and medication possession ratio during long-term Elexacaftor/Tezacaftor/Ivacaftor therapy in adolescents and young adults with cystic fibrosis
Introduction Elexacaftor/tezacaftor/ivacaftor (ETI) sustainably improves lung function (FEV₁), quality of life and sweat chloride (SC) levels in people with cystic fibrosis (pwCF). Psychological comorbidities may impair treatment adherence. This study assessed ETI adherence using SC and medication possession ratio (MPR...