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M. Lotfollahi

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Open access Aug 2026

G2T: Tissue Reconstruction from Gene Expression via Embedding-Distance Flow Matching

Single-cell RNA sequencing (scRNA-seq) profiles transcriptomes at high resolution but discards the spatial context of cells within a tissue—information that is essential for studying intercellular mechanisms and tissue architecture. Spatial transcriptomics (ST) retains coordinates but, depending on the assay, trades th...

Sebastian Birk, Fabian J. Theis, M. Lotfollahi · 0 citations

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