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Open access Sep 2026

Intravenous alteplase compared with standard medical treatment for stroke aged over 70 years: a secondary analysis of the HOPE randomised clinical trial.

BACKGROUND Data regarding intravenous alteplase in elderly patients with acute ischaemic stroke during 4.5 to 24 hours of onset are limited. This study aimed to investigate the effectiveness and safety of intravenous alteplase in patients aged over 70 years between 4.5 and 24 hours enrolled from the Treatment With Intr...

Yao-De He, Y. Zhou, Chang-Cai Meng et al. · 0 citations

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