Paracrine fibroblast–endothelial dialogue promotes pulmonary vascular remodeling in cardiometabolic HFpEF
Pulmonary hypertension (PH) is a common complication of heart failure with preserved ejection fraction (HFpEF) and is associated with worse outcomes than HFpEF alone. Beyond hemodynamic stress, maladaptive remodeling of the lung microenvironment driven by dysfunctional cellular populations may promote pulmonary m...