Background.
The evolving modalities of systemic treatment for non-small cell lung cancer (NSCLC) promotes the need to redefine different strategies for combined treatment in stage III and borderline-resectable lung cancer. Hereby we present the outcomes of a neoadjuvant chemo-immunotherapy regimen with subsequent in...
Y. Esakov, O. A. Kuchevskaya, I. Pokataev et al.· Malignant tumours· 0 citations
Introduction.
Deficiency of the mismatch repair system (dMMR) and microsatellite instability (MSI) occur in only 4–5% of patients with metastatic colorectal cancer (mCRC), but this molecular subgroup is characterized by high sensitivity to immune checkpoint inhibitors. Data on the efficacy and safety of such thera...
M. Lyadova, O. N. Zauzolkov, Julia S. Mansurova et al.· Meditsinskiy sovet = Medical...· 0 citations
The frequency and distribution of common, clinically relevant, and rare DPYD variants in a Russian cohort of patients receiving fluoropyrimidine-containing chemotherapy and the observed allele frequencies with European and East Asian reference populations are compared.
D. Fedorinov, V. Lyadov, M. Lyadova et al.· Genes· 0 citations
The combination of atezolizumab with platinum-based chemotherapy and etoposide as a first-line treatment for SCLC demonstrates high efficacy and an acceptable safety profile in real-world clinical settings.
Julia S. Mansurova, M. Lyadova, E. A. Denisova et al.· Journal of Modern Oncology· 0 citations
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