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Author

M. Mahdavinia

2 papers indexed here

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Open access Sep 2026

Ketotifen attenuates paraquat-induced nephrotoxicity in mice via suppression of oxidative stress and inflammation.

Background and purpose Paraquat (PQ) is a toxic herbicide to humans and animals that causes kidney damage. Ketotifen (KTF) is a first-generation antihistamine and a potent mast cell stabilizer with antioxidant and anti-inflammatory properties. This study aimed to evaluate the protective effect of KTF against PQ-induced...

A. Vadizadeh, M. Badiee, Ali Hasan Rahmani et al. · 0 citations
2026

Involvement of SIRT3 downstream targets ANT1, VDAC, CYPD, and Drp1 in a rat model of hepatic encephalopathy: Therapeutic role of thymoquinone

Objective(s): Hepatic encephalopathy (HE) is a brain disorder linked to hyperammonemia from liver injury. Elevated ammonia levels are known to impair mitochondrial function, the primary energy source for cells. Therefore, this study aimed to evaluate energy-related signaling pathways enhancing mitochondrial biogenesis...

Somayeh Hajipour, M. Dehghani, A. Sarkaki et al. · 0 citations

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