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M. Mahmood

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Open access Sep 2026

Autophagy regulates the function of myeloid-derived suppressor cells in tumor-induced immunosuppression

Tumor-infiltrating MDSCs were isolated from syngeneic C57BL/6 mouse models bearing B16-F10 melanoma or EO771 breast carcinoma tumors. Immunofluorescence staining of LC3B and western blotting of p62/SQSTM1 were used to assess autophagic activity. T-cell suppression by MDSCs was evaluated using co-culture assays, includi...

H. Kahya, Riyadh Khalaf Faris, M. Mahmood · 0 citations

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