Author

M. Manz

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Review Open access Aug 2026

IL-1-mediated cancer-adapted hematopoiesis in aging and clonal hematopoiesis.

Evidence is presented for the IL-1 pathway as a central driver of CAH acting both as a direct and indirect agent between tumors and HSPCs, further highlighting its pathological and thus targetable role in cancer progression.

Francisco Caiado, Nagihan G. Gonullu, M. Manz · Seminars in Immunology · 0 citations

Open access Jul 2026

A tumor profiling resource for ovarian cancer: insights into chemotherapy-driven heterogeneity and personalized treatment strategy

It is demonstrated that integrated multimodal tumor profiling can inform personalized maintenance treatment decisions and that chemotherapy reshapes tumor cell diversity.

Francis Jacob, R. Wegmann, Joanna Ficek-Pascual et al. · Nature Communications · 0 citations