Open access
Oct 2026
Stepwise intensification of guideline-directed medical therapy is associated with reduced major adverse kidney events in patients with HFpEF and diabetes
Diabetes mellitus is the leading cause of chronic kidney disease and is strongly associated with cardiovascular and all-cause mortality. Heart failure with preserved ejection fraction (HFpEF) frequently coexists with diabetes and confers high cardiorenal risk. Contemporary management of diabetic kidney disease is...
Y. Hoshika, Y. Kubota, T. Nishino et al.
· European Heart Journal · 0 citations