Author

Marta Moreno-Torres

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Open access Sep 2026

Mitochondrial membrane lipid cardiolipin controls fiber-type adaptations in aging muscle via estrogen-related receptor γ

Aging paradoxically leads to both a decline in skeletal muscle mitochondrial function and a shift in muscle composition that favors fibers rich in mitochondria. Yet the biological rationale and mechanism underlying this phenomenon remain largely unknown. Here we show that synthesis of the mitochondrial membrane lipid,...

Fabian Finger, Mikkel Frost, Shinya Watanabe et al. · Nature Aging · 1 citation

Open access Sep 2026

Network propagation in bipartite metabolite–reaction graphs for metabolomic data exploration

Interpretation of metabolomic data is frequently limited by incomplete metabolite coverage and the predefined representation of biochemical organization provided by pathway-based approaches. This study describes and evaluates a graph-based network propagation method designed to faciitate metabolomic data exploration by...

J. Kuligowski, Marta Moreno-Torres, D. Pérez-Guaita et al. · Metabolomics · 0 citations

Open access Jul 2026

The aryl hydrocarbon receptor is downregulated in MASLD while its activation attenuates steatosis in human hepatocytes through an IGFBP1-associated pathway.

It is demonstrated that AHR expression and its canonical activity-assessed by CYP1A1 mRNA levels-are inversely correlated with hepatic steatosis, and activation of this pathway may be taken into account in the therapeutic approaches for MASLD.

Marta Del Pozo-Medina, P. Soluyanova, Eugenia Pareja et al. · Archives of Toxicology · 0 citations