Obesity is projected to affect about one billion adults by 2030 and is associated with cardiometabolic morbidity. Orforglipron is an oral, non-peptide glucagon-like peptide-1 receptor agonist developed to provide weight and metabolic benefits. Prior meta-analyses have supported its efficacy and safety but were limited...
Mohamed Gamal Hegaz, Mohammad Yassin Al Aboud, Abanoub I. I. Kamel et al.· BMC Endocrine Disorders· 0 citations
BACKGROUND
Baxdrostat, a selective aldosterone synthase inhibitor, has emerged as a novel therapy for uncontrolled or resistant hypertension; however, randomized controlled trials (RCTs) have shown variable results.
OBJECTIVE
To evaluate the efficacy and safety of baxdrostat compared with placebo or standard care in...
Muhammad Burhan, Z. Shahid, M. Naveed et al.· The Annals of Pharmacotherap...· 0 citations
Patients with T2DM undergoing TAVR demonstrate higher risks of all‐cause mortality, MACCE, and HF exacerbation compared to their counterparts without T2DM.
The T2DM cohort also demonstrated higher all‐cause readmissions, mechanical ventilation, and renal replacement therapy compared to patients without T2D...
Hritvik Jain, Nandan Patel, M. Naveed et al.· Catheterization and cardiova...· 0 citations
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