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Open access Aug 2026

Pseudotime analysis of 2,106 brains across nine regions reveals conserved immune, neuronal, and myelin regulatory programs in Alzheimer’s disease

A conserved transcriptional architecture underlying AD progression is revealed, organized around coordinated immune activation, synaptic loss, and myelin remodeling, with the cerebellum following a distinct trajectory.

F. Ecca, S. Song, M. Naymik et al. · 0 citations

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