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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

M. Nieuwland

h-index 20 View on Semantic Scholar

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Sep 2026

Pre-existing immunity and hrHPV status determine immunotherapy response in advanced penile cancer: biomarkers and overall survival in the PERICLES trial.

Penile squamous cell carcinoma (PeSCC) is a rare malignancy with limited treatment options in advanced stages. The phase II PERICLES trial (NCT03686332) investigated atezolizumab with or without radiotherapy in advanced penile cancer. Here, we report mature overall survival (OS) and updated progression-free survival (P...

T. Rafael, Alberto Gil-Jimenez, L. Elst et al. · 0 citations
Open access Sep 2026

A spatial single-cell transcriptomic atlas of metastatic breast cancer progression

Metastatic breast cancer represents a major societal burden and is a main cause of cancer-related death in women, with limited rationale-based treatment options and often dismal outcomes. Intra-tumor heterogeneity, tumor-stromal interactions and clonal selection are considered to play a major role in metastasis formati...

Z. Dauyey, A. Velds, R. Gobits et al. · 0 citations
Open access Aug 2026

Proteomics of human cancer-associated T cells identifies regulators of T cell functionality

Integrated multi-omic profiling of human tumor-infiltrating T cells reveals cell-intrinsic regulators of T cell dysfunction that are missed by transcriptomic analyses alone, highlighting an additional layer of regulatory control.

Kaspar Bresser, Zan Hozjan, N. Servaas et al. · 0 citations

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