To respond to protein misfolding in the endoplasmic reticulum (ER), cells trigger the unfolded protein response (UPR) to re-establish proteostasis. However, unresolved UPR results in chronic ER stress, which is critical to the development and advancement of type 2 diabetes mellitus (T2DM), a multifactorial disease whos...
O. T. Obafemi, A. Ayeleso, B. E. Ekundayo et al.· Molecular Biology Reports· 0 citations
Morin (3,5,7,2′,4′‐pentahydroxyflavone) is a dietary flavonol with broad neuroprotective, anti‐inflammatory, and antioxidant actions across central and peripheral nervous system models. This synthesis consolidates evidence from in vitro and rodent studies—covering neurodegenerative proteinopathies (Alzheimer's, Parkins...
B. E. Ekundayo, Motunrayo Comfort Ekundayo, S. Alonge et al.· European Journal of Neurosci...· 0 citations
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