Open access
Aug 2026
PIWI proximity proteome reveals Set1-mediated piRNA biogenesis for transposon silencing at telomeres.
Systemically characterize the proximity proteome of the PIWI members Piwi, Aubergine (Aub), and Ago3 in the germline of Drosophila ovaries and uncover a noncanonical function of Set1 in Piwi-mediated TE silencing in germline nuclei.
Wakana Isshiki, H. Kozuka-Hata, M. Oyama et al.
· EMBO Reports · 0 citations