A multi-reader multi-case framework for evaluating the decision impact of emerging diagnostic tests for lung cancer.
We assessed the feasibility of a multi-reader, multi-case (MRMC) observer-performance design to evaluate the simulated decision impact of a radiomics-based computer-assisted diagnostic tool (CADx) and a methylated circulating tumour DNA (ctDNA) assay in lung cancer work-up. Patients referred to a Danish fast-track lung...