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Open access Sep 2026

Prognostic value of hormone receptor expression in patients with HR+/HER2− advanced BC treated with first-line ET+CDK4/6i: results from the multicentre observational, real-world PALMARES-2 study

Effectiveness of first-line ET plus CDK4/6i in patients with HR+/HER2− aBC worsens progressively with decreasing ERα expression, and PgR expression adds further prognostic discrimination, with low ERα and PgR expression identifying a subgroup of patients with particularly poor outcomes.

F. Ligorio, L. Provenzano, R. Caputo et al. · 0 citations
Open access Sep 2026

AI-Enhanced PROMs and Drug-Drug Interaction Screening in Advanced Breast Cancer: Protocol of a Prospective Observational Pilot Study

BackgroundIn advanced breast cancer, treatment pathways are becoming increasingly prolonged and complex across different biological subtypes. New systemic and targeted therapies require long-term monitoring and careful personalization according to patient-specific factors that demand increasingly individualized therape...

O. Tinelli, C. von Arx, R. Caputo et al. · 0 citations

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