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M. Puzianowska-Kuźnicka

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Review Open access Jul 2026

What Do We Know About Immune System Aging from Human and Animal Studies?

Age-related alterations in the function of primary and secondary lymphoid organs, including the bone marrow, thymus, spleen, and lymph nodes are summarized, which include a decline in naïve cell populations, an accumulation of memory and exhausted cells, and a reduction in the diversity of antigen receptors.

Marta Cąkała-Jakimowicz, A. Domaszewska-Szostek, M. Puzianowska-Kuźnicka · 0 citations