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Open access Sep 2026

Effects of Liraglutide and Semaglutide on Cardiometabolic Dysregulation and Oxidative Stress in an Experimental Model of Metabolic Syndrome

Background/Objectives: Metabolic syndrome (MetS) increases susceptibility to myocardial ischemia/reperfusion (I/R) injury through metabolic disturbance, hypertension, and oxidative stress. This study aimed to compare the effects of liraglutide and semaglutide on post-ischemic cardiac function, oxidative stress, and his...

M. Ravić, I. Srejović, M. Andjic et al. · 0 citations
Review Sep 2026

CARDIOVASCULAR EFFECTS OF INCRETIN RECEPTOR AGONISTS: BEYOND GLYCEMIC CONTROL.

Incretin-based therapies have evolved from selective GLP-1RA to dual GLP-1/ GIP agonists and unimolecular triple GLP-1/GIP/glucagon receptor agonists. This review examines the cardiovascular effects of these three pharmacological tiers, with emphasis on mechanisms that operate beyond glycaemic control. Mediation analys...

M. Ravić, I. Srejović, I. Milosavljević et al. · 0 citations

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