Association of Metabolic Syndrome with Chronic Obstructive Pulmonary Disease (COPD)
Background: Chronic obstructive pulmonary disease (COPD) is thought to have increased association with metabolic syndrome (MS) which represents a cluster of factors that increase the risk of cardiovascular diseases and diabetes mellitus. However, the extent of association of COPD with MS and its individual components are still an unsettled issue, and it is likely to vary from population to population. This study was undertaken to assess association of COPD with metabolic syndrome. Methods: This cross-sectional study conducted at the Department of Respiratory Medicine in National Institute of Diseases of the Chest and Hospital from January 2019–December 2019. A total of 91 patients with chronic obstructive pulmonary disease (COPD) were enrolled in this study. Results: Out of 91 patients with COPD, more than one third (34.1%) patients were belonged to age 51-60 & 61-70 years respectively with mean age 60.4±10.9 years ranging from 42 to 90 years. Majority (85.7%) patients were male. Male to female ratio was 6:1. Twenty seven (29.7%) were service holder and most of the patients 76(83.5%) were smoker. Mean BMI was 20.6±4.0 kg/m2, mean waist circumference was 86.9±6.8 cm, mean SBP 120.1±17.5 mmHg and mean DBP 76.3±11.1 mmHg. Mean FEV1/FVC post bronchodilator was 51.2±9.5 percent. Mean triglycerides was 149.9±38.4 mg/dl, mean HDL-C was 39.4±9.8 mg/dl, mean fasting glucose was 104.1±28.0 mg/dl. Metabolic syndrome was found in 19(20.9%) patients. Age, sex, occupational status, smoking, BMI, waist circumference, hypertension, triglycerides, HDL-C, fasting glucose and metabolic syndrome were not statistically significant (p>0.05) when compared grade of COPD. Conclusion: In conclusion, the present study demonstrated that metabolic syndrome present in 20.9% of COPD patients. Age, sex, occupational status, smoking, BMI, waist circumference, hypertension, triglycerides, HDL-C, fasting glucose and metabolic syndrome were not statistically significant when compared grade of COPD. Thus, considering COPD as a systemic disease and screening for components of metabolic syndrome could form a part of routine work-up of these patients. Chest Heart J. 2022; 46(1) : 10-17