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Open access Oct 2026

The host transcriptional response to real-world cryptococcosis in the setting of advanced HIV disease defines dysregulated immune responses that underlie increased vulnerability to infection

Background Cryptococcus causes life-threatening infections; however, immune programs driving pathogenesis of these infections in the human host remain incompletely described. We leveraged whole-blood transcriptomic analysis to define distinct, conserved elements of the host immune response in participants with cryptoco...

B. Sim, J. Steinbrink, Cameron Miller et al. · 0 citations
Open access Aug 2026

Investigating Bacillus anthracis genomic diversity and trait-specific lineages in an endemic area in northern Tanzania through a combination of traditional and culture-free sequencing approaches

This study characterises the genomic diversity of BA in an endemic area, the Ngorongoro Conservation Area (NCA), in northern Tanzania and demonstrates unexpectedly high BA strain diversity and limited population structure in this endemic area across a range of spatial scales.

A. Hilbig, M. Medvecky, Tiziana Lembo et al. · 0 citations

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