Open access
Sep 2026
Development and Optimisation Using D-Optimal Design of Dual-Functionalized Hyaluronic Acid-Chitosan-Coated Mesoporous Silica Nanoparticles for Repurposed Propranolol Delivery in Breast Cancer: A Proof-of-Concept Study.
Proof of concept is provided that HA-CH-coated mesoporous silica nanoparticles enhance the in vitro anticancer activity of repurposed propranolol through encapsulation and controlled release, laying the foundation for future investigation of HA-mediated cellular targeting.
M. S. Ibrahim, N. Elsayyad, S. H. Noshi
· Pharmaceutical development a... · 0 citations